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Discovery and structural optimization of 3-O-β-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections

Currently, SARS-CoV-2 virus is an emerging pathogen that has posed a serious threat to public health worldwide. However, no agents have been approved to treat SARS-CoV-2 infections to date, underscoring the great need for effective and practical therapies for SARS-CoV-2 outbreaks. We reported that a...

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Detalles Bibliográficos
Autores principales: Li, Hui, Cheng, Chen, Li, Sumei, Wu, Yan, Liu, Zhihao, Liu, Mingjian, Chen, Jianxin, Zhong, Qiuyu, Zhang, Xuesha, Liu, Shuwen, Song, Gaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869707/
https://www.ncbi.nlm.nih.gov/pubmed/33588180
http://dx.doi.org/10.1016/j.ejmech.2021.113242