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Overactivation of the IGF signalling pathway in osteosarcoma: a potential therapeutic target?

Osteosarcoma is the most common primary malignant bone tumour in children and adolescents. More than a third of patients do not respond to standard therapy and urgently require alternative treatment options. Due to a high degree of inter‐ and intra‐tumoural genomic heterogeneity and complexity, recu...

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Detalles Bibliográficos
Autores principales: Ameline, Baptiste, Kovac, Michal, Nathrath, Michaela, Barenboim, Maxim, Witt, Olaf, Krieg, Andreas H, Baumhoer, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869926/
https://www.ncbi.nlm.nih.gov/pubmed/33295144
http://dx.doi.org/10.1002/cjp2.191