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Aedes aegypti mosquito saliva ameliorates acetaminophen-induced liver injury in mice

Acetaminophen (N-acetyl-p-aminophenol, APAP) overdose is the most common cause of drug-induced liver injury (DILI). Although the primary hepatic damage is induced by APAP-derived toxic intermediates resulting from cytochrome P450 metabolism, immune components also play an important role in DILI path...

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Detalles Bibliográficos
Autores principales: Assis, Josiane B., Cogliati, Bruno, Esteves, Eliane, Capurro, Margareth L., Fonseca, Denise M., Sá-Nunes, Anderson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869984/
https://www.ncbi.nlm.nih.gov/pubmed/33556084
http://dx.doi.org/10.1371/journal.pone.0245788