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Mathematical modelling of oxygen gradients in stem cell-derived liver tissue
A major bottleneck in the study of human liver physiology is the provision of stable liver tissue in sufficient quantity. As a result, current approaches to modelling human drug efficacy and toxicity rely heavily on immortalized human and animal cell lines. These models are informative but do posses...
Autores principales: | Leedale, Joseph A., Lucendo-Villarin, Baltasar, Meseguer-Ripolles, Jose, Kasarinaite, Alvile, Webb, Steven D., Hay, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870006/ https://www.ncbi.nlm.nih.gov/pubmed/33556073 http://dx.doi.org/10.1371/journal.pone.0244070 |
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