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One is not enough: On the effects of reference genome for the mapping and subsequent analyses of short-reads
Mapping of high-throughput sequencing (HTS) reads to a single arbitrary reference genome is a frequently used approach in microbial genomics. However, the choice of a reference may represent a source of errors that may affect subsequent analyses such as the detection of single nucleotide polymorphis...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870062/ https://www.ncbi.nlm.nih.gov/pubmed/33503026 http://dx.doi.org/10.1371/journal.pcbi.1008678 |