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One is not enough: On the effects of reference genome for the mapping and subsequent analyses of short-reads

Mapping of high-throughput sequencing (HTS) reads to a single arbitrary reference genome is a frequently used approach in microbial genomics. However, the choice of a reference may represent a source of errors that may affect subsequent analyses such as the detection of single nucleotide polymorphis...

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Detalles Bibliográficos
Autores principales:	Valiente-Mullor, Carlos, Beamud, Beatriz, Ansari, Iván, Francés-Cuesta, Carlos, García-González, Neris, Mejía, Lorena, Ruiz-Hueso, Paula, González-Candelas, Fernando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870062/ https://www.ncbi.nlm.nih.gov/pubmed/33503026 http://dx.doi.org/10.1371/journal.pcbi.1008678

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