Cargando…

Early life imprints the hierarchy of T cell clone sizes

The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors. While clonal selection in response to particular antigens has been studied in detail, it is unknown how a lifetime of exposures to many antigens collectively shape the immune repertoire. Here, usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaimann, Mario U, Nguyen, Maximilian, Desponds, Jonathan, Mayer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870140/
https://www.ncbi.nlm.nih.gov/pubmed/33345776
http://dx.doi.org/10.7554/eLife.61639