A Priori Activation of Apoptosis Pathways of Tumor (AAAPT) technology: Development of targeted apoptosis initiators for cancer treatment

Cancer cells develop tactics to circumvent the interventions by desensitizing themselves to interventions. Amongst many, the principle routes of desensitization include a) activation of survival pathways (e.g. NF-kB, PARP) and b) downregulation of cell death pathways (e.g. CD95/CD95L). As a result,...

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Detalles Bibliográficos
Autores principales: Pandurangi, Raghu S., Tomasetti, Marco, Verapazham, Sekar T., Paulmurugan, Ramasamy, Ma, Cynthia, Rajput, Sandeep, Anjanappa, Manjushree, Nakshatri, Harikrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870153/
https://www.ncbi.nlm.nih.gov/pubmed/33556062
http://dx.doi.org/10.1371/journal.pone.0225869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870153/
https://www.ncbi.nlm.nih.gov/pubmed/33556062
http://dx.doi.org/10.1371/journal.pone.0225869

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