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Rapamycin Treatment of Tendon Stem/Progenitor Cells Reduces Cellular Senescence by Upregulating Autophagy

The elderly population is prone to tendinopathy due to aging-related tendon changes such as cellular senescence and a decreased ability to modulate inflammation. Aging can render tendon stem/progenitor cells (TSCs) into premature senescence. We investigated the effects of rapamycin, a specific mTOR...

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Detalles Bibliográficos
Autores principales: Nie, Daibang, Zhang, Jianying, Zhou, Yiqin, Sun, Jiuyi, Wang, Wang, Wang, James H.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870298/
https://www.ncbi.nlm.nih.gov/pubmed/33603790
http://dx.doi.org/10.1155/2021/6638249