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Corydalis Saxicola Bunting Total Alkaloids Attenuate Walker 256-Induced Bone Pain and Osteoclastogenesis by Suppressing RANKL-Induced NF-κB and c-Fos/NFATc1 Pathways in Rats

Metastatic bone pain is characterized by insufferable bone pain and abnormal bone structure. A major goal of bone cancer treatment is to ameliorate osteolytic lesion induced by tumor cells. Corydalis saxicola Bunting total alkaloids (CSBTA), the alkaloid compounds extracted from the root of C. saxic...

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Detalles Bibliográficos
Autores principales: Ju, Linjie, Hu, Peipei, Chen, Ping, Wu, Jiejie, Li, Zhuoqun, Qiu, Zhixia, Cheng, Jun, Huang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870471/
https://www.ncbi.nlm.nih.gov/pubmed/33574755
http://dx.doi.org/10.3389/fphar.2020.609119