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COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology
Smell and taste impairments are recognized as common symptoms in COVID 19 patients even in an asymptomatic phase. Indeed, depending on the country, in up to 85–90% of cases anosmia and dysgeusia are reported. We will review briefly the main mechanisms involved in the physiology of olfaction and tast...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870487/ https://www.ncbi.nlm.nih.gov/pubmed/33574768 http://dx.doi.org/10.3389/fphys.2020.625110 |
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author | Meunier, Nicolas Briand, Loïc Jacquin-Piques, Agnès Brondel, Laurent Pénicaud, Luc |
author_facet | Meunier, Nicolas Briand, Loïc Jacquin-Piques, Agnès Brondel, Laurent Pénicaud, Luc |
author_sort | Meunier, Nicolas |
collection | PubMed |
description | Smell and taste impairments are recognized as common symptoms in COVID 19 patients even in an asymptomatic phase. Indeed, depending on the country, in up to 85–90% of cases anosmia and dysgeusia are reported. We will review briefly the main mechanisms involved in the physiology of olfaction and taste focusing on receptors and transduction as well as the main neuroanatomical pathways. Then we will examine the current evidences, even if still fragmented and unsystematic, explaining the disturbances and mode of action of the virus at the level of the nasal and oral cavities. We will focus on its impact on the peripheral and central nervous system. Finally, considering the role of smell and taste in numerous physiological functions, especially in ingestive behavior, we will discuss the consequences on the physiology of the patients as well as management regarding food intake. |
format | Online Article Text |
id | pubmed-7870487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78704872021-02-10 COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology Meunier, Nicolas Briand, Loïc Jacquin-Piques, Agnès Brondel, Laurent Pénicaud, Luc Front Physiol Physiology Smell and taste impairments are recognized as common symptoms in COVID 19 patients even in an asymptomatic phase. Indeed, depending on the country, in up to 85–90% of cases anosmia and dysgeusia are reported. We will review briefly the main mechanisms involved in the physiology of olfaction and taste focusing on receptors and transduction as well as the main neuroanatomical pathways. Then we will examine the current evidences, even if still fragmented and unsystematic, explaining the disturbances and mode of action of the virus at the level of the nasal and oral cavities. We will focus on its impact on the peripheral and central nervous system. Finally, considering the role of smell and taste in numerous physiological functions, especially in ingestive behavior, we will discuss the consequences on the physiology of the patients as well as management regarding food intake. Frontiers Media S.A. 2021-01-26 /pmc/articles/PMC7870487/ /pubmed/33574768 http://dx.doi.org/10.3389/fphys.2020.625110 Text en Copyright © 2021 Meunier, Briand, Jacquin-Piques, Brondel and Pénicaud. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Meunier, Nicolas Briand, Loïc Jacquin-Piques, Agnès Brondel, Laurent Pénicaud, Luc COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology |
title | COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology |
title_full | COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology |
title_fullStr | COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology |
title_full_unstemmed | COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology |
title_short | COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology |
title_sort | covid 19-induced smell and taste impairments: putative impact on physiology |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870487/ https://www.ncbi.nlm.nih.gov/pubmed/33574768 http://dx.doi.org/10.3389/fphys.2020.625110 |
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