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2-NPPA Mitigates Osteoclastogenesis via Reducing TRAF6-Mediated c-fos Expression

Excessive bone resorption leads to bone destruction in pathological bone diseases. Osteoporosis, which occurs when osteoclast-mediated bone resorption exceeds osteoblast-mediated bone synthesis, is regarded a global health challenge. Therefore, it is of great importance to identify agents that can r...

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Detalles Bibliográficos
Autores principales: Chen, Zhihao, Ding, Mina, Cho, Eunjin, Seong, Jihyoun, Lee, Sunwoo, Lee, Tae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870508/
https://www.ncbi.nlm.nih.gov/pubmed/33574753
http://dx.doi.org/10.3389/fphar.2020.599081