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Mitochondria exert age-divergent effects on recovery from spinal cord injury

The extent that age-dependent mitochondrial dysfunction drives neurodegeneration is not well understood. This study tested the hypothesis that mitochondria contribute to spinal cord injury (SCI)-induced neurodegeneration in an age-dependent manner by using 2,4-dinitrophenol (DNP) to uncouple electro...

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Detalles Bibliográficos
Autores principales: Stewart, Andrew N., McFarlane, Katelyn E., Vekaria, Hemendra J., Bailey, William M., Slone, Stacey A., Tranthem, Lauren A., Zhang, Bei, Patel, Samir P., Sullivan, Patrick G., Gensel, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870583/
https://www.ncbi.nlm.nih.gov/pubmed/33422552
http://dx.doi.org/10.1016/j.expneurol.2021.113597