Osthole Alleviates Neointimal Hyperplasia in Balloon-Induced Arterial Wall Injury by Suppressing Vascular Smooth Muscle Cell Proliferation and Downregulating Cyclin D1/CDK4 and Cyclin E1/CDK2 Expression

Percutaneous coronary intervention (PCI) is the most widely used therapy for treating ischemic heart disease. However, intimal hyperplasia and restenosis usually occur within months after angioplasty. Modern pharmacological researchers have proven that osthole, the major active coumarin of Cnidium m...

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Detalles Bibliográficos
Autores principales: Li, Yi-Qi, Li, Ye-Li, Li, Xiao-Tong, Lv, Jun-Yuan, Gao, Yang, Li, Wen-Na, Gong, Qi-Hai, Yang, Dan-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870719/
https://www.ncbi.nlm.nih.gov/pubmed/33574763
http://dx.doi.org/10.3389/fphys.2020.514494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870719/
https://www.ncbi.nlm.nih.gov/pubmed/33574763
http://dx.doi.org/10.3389/fphys.2020.514494

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