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Osthole Alleviates Neointimal Hyperplasia in Balloon-Induced Arterial Wall Injury by Suppressing Vascular Smooth Muscle Cell Proliferation and Downregulating Cyclin D1/CDK4 and Cyclin E1/CDK2 Expression
Percutaneous coronary intervention (PCI) is the most widely used therapy for treating ischemic heart disease. However, intimal hyperplasia and restenosis usually occur within months after angioplasty. Modern pharmacological researchers have proven that osthole, the major active coumarin of Cnidium m...
Autores principales: | Li, Yi-Qi, Li, Ye-Li, Li, Xiao-Tong, Lv, Jun-Yuan, Gao, Yang, Li, Wen-Na, Gong, Qi-Hai, Yang, Dan-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870719/ https://www.ncbi.nlm.nih.gov/pubmed/33574763 http://dx.doi.org/10.3389/fphys.2020.514494 |
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