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Comparing in vitro human liver models to in vivo human liver using RNA-Seq

The liver plays an important role in xenobiotic metabolism and represents a primary target for toxic substances. Many different in vitro cell models have been developed in the past decades. In this study, we used RNA-sequencing (RNA-Seq) to analyze the following human in vitro liver cell models in c...

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Detalles Bibliográficos
Autores principales: Gupta, Rajinder, Schrooders, Yannick, Hauser, Duncan, van Herwijnen, Marcel, Albrecht, Wiebke, ter Braak, Bas, Brecklinghaus, Tim, Castell, Jose V., Elenschneider, Leroy, Escher, Sylvia, Guye, Patrick, Hengstler, Jan G., Ghallab, Ahmed, Hansen, Tanja, Leist, Marcel, Maclennan, Richard, Moritz, Wolfgang, Tolosa, Laia, Tricot, Tine, Verfaillie, Catherine, Walker, Paul, van de Water, Bob, Kleinjans, Jos, Caiment, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870774/
https://www.ncbi.nlm.nih.gov/pubmed/33106934
http://dx.doi.org/10.1007/s00204-020-02937-6