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Kinetics of humoral deficiency in CART19-treated children and young adults with acute lymphoblastic leukaemia

CD19-CAR T-cell therapy (CART19) causes B-cell aplasia (BCA) and dysgammaglobulinemia but there is a lack of information about the degree of its secondary immunodeficiency. We conducted a prospective study in children and young adults with acute lymphoblastic leukaemia treated with CART19, analysing...

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Detalles Bibliográficos
Autores principales: Deyà-Martínez, A., Alonso-Saladrigues, A., García, A. P., Faura, A., Torrebadell, M., Vlagea, A., Català, A., Esteve-Solé, A., Juan, M., Rives, S., Alsina, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870804/
https://www.ncbi.nlm.nih.gov/pubmed/32801317
http://dx.doi.org/10.1038/s41409-020-01027-6