The GSK3β-β-catenin-TCF1 pathway improves naive T cell activation in old adults by upregulating miR-181a

MicroRNAs play an important role in the regulation of T cell development, activation, and differentiation. One of the most abundant microRNAs in lymphocytes is miR-181a, which controls T cell receptor (TCR) activation thresholds in thymic selection as well as in peripheral T cell responses. We previ...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Zhongde, Gould, Timothy M., Zhang, Huimin, Jin, Jun, Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870817/
https://www.ncbi.nlm.nih.gov/pubmed/33558531
http://dx.doi.org/10.1038/s41514-021-00056-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870817/
https://www.ncbi.nlm.nih.gov/pubmed/33558531
http://dx.doi.org/10.1038/s41514-021-00056-9

Ejemplares similares