HMGB1 orchestrates STING-mediated senescence via TRIM30α modulation in cancer cells

Although cellular senescence has emerged as a novel therapeutic concept in cancer, its underlying mechanisms remain unclear. High mobility group box 1 (HMGB1) and stimulator of interferon genes (STING) are involved in senescence. However, their interactions in senescence have not been reported. Ther...

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Detalles Bibliográficos
Autores principales: Lee, Je-Jung, Park, In Ho, Kwak, Man Sup, Rhee, Woo Joong, Kim, Songhee H., Shin, Jeon-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870821/
https://www.ncbi.nlm.nih.gov/pubmed/33558529
http://dx.doi.org/10.1038/s41420-021-00409-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870821/
https://www.ncbi.nlm.nih.gov/pubmed/33558529
http://dx.doi.org/10.1038/s41420-021-00409-z

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