Cargando…
HMGB1 orchestrates STING-mediated senescence via TRIM30α modulation in cancer cells
Although cellular senescence has emerged as a novel therapeutic concept in cancer, its underlying mechanisms remain unclear. High mobility group box 1 (HMGB1) and stimulator of interferon genes (STING) are involved in senescence. However, their interactions in senescence have not been reported. Ther...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870821/ https://www.ncbi.nlm.nih.gov/pubmed/33558529 http://dx.doi.org/10.1038/s41420-021-00409-z |