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Winner-takes-all resource competition redirects cascading cell fate transitions

Failure of modularity remains a significant challenge for assembling synthetic gene circuits with tested modules as they often do not function as expected. Competition over shared limited gene expression resources is a crucial underlying reason. It was reported that resource competition makes two se...

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Detalles Bibliográficos
Autores principales: Zhang, Rong, Goetz, Hanah, Melendez-Alvarez, Juan, Li, Jiao, Ding, Tian, Wang, Xiao, Tian, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870843/
https://www.ncbi.nlm.nih.gov/pubmed/33558556
http://dx.doi.org/10.1038/s41467-021-21125-3