Non-linearity of end-systolic pressure–volume relation in afterload increases is caused by an overlay of shortening deactivation and the Frank–Starling mechanism

The linearity and load insensitivity of the end-systolic pressure–volume-relationship (ESPVR), a parameter that describes the ventricular contractile state, are controversial. We hypothesize that linearity is influenced by a variable overlay of the intrinsic mechanism of autoregulation to afterload...

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Detalles Bibliográficos
Autores principales: Habigt, Moriz A., Krieger, Michelle, Gesenhues, Jonas, Ketelhut, Maike, Mechelinck, Mare, Hein, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870877/
https://www.ncbi.nlm.nih.gov/pubmed/33558620
http://dx.doi.org/10.1038/s41598-021-82791-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870877/
https://www.ncbi.nlm.nih.gov/pubmed/33558620
http://dx.doi.org/10.1038/s41598-021-82791-3

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