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Computer modeling of whole-cell voltage-clamp analyses to delineate guidelines for good practice of manual and automated patch-clamp

The patch-clamp technique and more recently the high throughput patch-clamp technique have contributed to major advances in the characterization of ion channels. However, the whole-cell voltage-clamp technique presents certain limits that need to be considered for robust data generation. One major c...

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Detalles Bibliográficos
Autores principales: Montnach, Jérôme, Lorenzini, Maxime, Lesage, Adrien, Simon, Isabelle, Nicolas, Sébastien, Moreau, Eléonore, Marionneau, Céline, Baró, Isabelle, De Waard, Michel, Loussouarn, Gildas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870888/
https://www.ncbi.nlm.nih.gov/pubmed/33558601
http://dx.doi.org/10.1038/s41598-021-82077-8