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Chronic modafinil therapy ameliorates depressive-like behavior, spatial memory and hippocampal plasticity impairments, and sleep-wake changes in a surgical mouse model of menopause

Depression, cognitive deficits, and sleep disturbances are common and often severe in menopausal women. Hormone replacement cannot effectively alleviate these symptoms and sometimes elicits life-threatening adverse reactions. Exploring effective therapies to target psychological problems is urgently...

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Detalles Bibliográficos
Autores principales: Yan, Yu-Dong, Chen, Yu-Qing, Wang, Chen-Yao, Ye, Chen-Bo, Hu, Zhen-Zhen, Behnisch, Thomas, Huang, Zhi-Li, Yang, Su-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870893/
https://www.ncbi.nlm.nih.gov/pubmed/33558464
http://dx.doi.org/10.1038/s41398-021-01229-6