Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA

Base-pairing interactions mediate many intermolecular target recognition events. Even a single base-pair mismatch can cause a substantial difference in activity but how such changes influence the target search kinetics in vivo is unknown. Here, we use high-throughput sequencing and quantitative supe...

Descripción completa

Detalles Bibliográficos
Autores principales: Poddar, Anustup, Azam, Muhammad S., Kayikcioglu, Tunc, Bobrovskyy, Maksym, Zhang, Jichuan, Ma, Xiangqian, Labhsetwar, Piyush, Fei, Jingyi, Singh, Digvijay, Luthey-Schulten, Zaida, Vanderpool, Carin K., Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870926/
https://www.ncbi.nlm.nih.gov/pubmed/33558533
http://dx.doi.org/10.1038/s41467-021-21144-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870926/
https://www.ncbi.nlm.nih.gov/pubmed/33558533
http://dx.doi.org/10.1038/s41467-021-21144-0

Ejemplares similares