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The origin of the expressed retrotransposed gene ACTBL2 and its influence on human melanoma cells’ motility and focal adhesion formation

We have recently found that β-actin-like protein 2 (actbl2) forms complexes with gelsolin in human melanoma cells and can polymerize. Phylogenetic and bioinformatic analyses showed that actbl2 has a common origin with two non-muscle actins, which share a separate history from the muscle actins. The...

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Detalles Bibliográficos
Autores principales: Malek, Natalia, Michrowska, Aleksandra, Mazurkiewicz, Ewa, Mrówczyńska, Ewa, Mackiewicz, Paweł, Mazur, Antonina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870945/
https://www.ncbi.nlm.nih.gov/pubmed/33558623
http://dx.doi.org/10.1038/s41598-021-82074-x