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1,25-(OH)(2)D(3) ameliorates renal interstitial fibrosis in UUO rats through the AMPKα/mTOR pathway
OBJECTIVE: To investigate the effects of 1,25(OH)(2)D(3) on renal fibrosis associated with the AMP-activated protein kinase (AMPK)α/mechanistic target of rapamycin (mTOR) signalling pathway in a rat model of unilateral ureteral obstruction (UUO). METHODS: A total of 54 male Sprague Dawley rats were...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871069/ https://www.ncbi.nlm.nih.gov/pubmed/33530801 http://dx.doi.org/10.1177/0300060520981360 |