Cargando…

1,25-(OH)(2)D(3) ameliorates renal interstitial fibrosis in UUO rats through the AMPKα/mTOR pathway

OBJECTIVE: To investigate the effects of 1,25(OH)(2)D(3) on renal fibrosis associated with the AMP-activated protein kinase (AMPK)α/mechanistic target of rapamycin (mTOR) signalling pathway in a rat model of unilateral ureteral obstruction (UUO). METHODS: A total of 54 male Sprague Dawley rats were...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Shasha, Yang, Xiaopeng, Wang, Jianwu, Luo, Jing, Guo, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871069/
https://www.ncbi.nlm.nih.gov/pubmed/33530801
http://dx.doi.org/10.1177/0300060520981360