Cargando…
1,25-(OH)(2)D(3) ameliorates renal interstitial fibrosis in UUO rats through the AMPKα/mTOR pathway
OBJECTIVE: To investigate the effects of 1,25(OH)(2)D(3) on renal fibrosis associated with the AMP-activated protein kinase (AMPK)α/mechanistic target of rapamycin (mTOR) signalling pathway in a rat model of unilateral ureteral obstruction (UUO). METHODS: A total of 54 male Sprague Dawley rats were...
Autores principales: | Tian, Shasha, Yang, Xiaopeng, Wang, Jianwu, Luo, Jing, Guo, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871069/ https://www.ncbi.nlm.nih.gov/pubmed/33530801 http://dx.doi.org/10.1177/0300060520981360 |
Ejemplares similares
-
Ruxolitinib Alleviates Renal Interstitial Fibrosis in UUO Mice
por: Bai, Yu, et al.
Publicado: (2020) -
Synthetic Non-Coding RNA for Suppressing mTOR Translation to Prevent Renal Fibrosis Related to Autophagy in UUO Mouse Model
por: Kim, Young-Ah, et al.
Publicado: (2022) -
Rapamycin Ameliorates Kidney Fibrosis by Inhibiting the Activation of mTOR Signaling in Interstitial Macrophages and Myofibroblasts
por: Chen, Guochun, et al.
Publicado: (2012) -
Hirudin Ameliorates Renal Interstitial Fibrosis via Regulating TGF-β1/Smad and NF-κB Signaling in UUO Rat Model
por: Yang, Kang, et al.
Publicado: (2020) -
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice
por: Zhou, Zhuanli, et al.
Publicado: (2020)