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Lipoxin A4 promotes autophagy and inhibits overactivation of macrophage inflammasome activity induced by Pg LPS

OBJECTIVE: To explore the role of lipoxin A4 (LXA4) on inflammasome and inflammatory activity in macrophages activated by Porphyromonas gingivalis lipopolysaccharide (PgLPS) one of the major causative agents of chronic periodontitis. METHODS: The mouse macrophage cell line RAW264.7 was used to produ...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Geng, Wenjing, Wan, Kefei, Guo, Kailei, Xi, Fengjun, Xu, Xiangqun, Xiong, Xiujuan, Huang, Xu, Liu, Jiayi, Kuang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871081/
https://www.ncbi.nlm.nih.gov/pubmed/33528285
http://dx.doi.org/10.1177/0300060520981259