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Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis

BACKGROUND: Synaptic failure is one of the principal events associated with cognitive dysfunction in Alzheimer’s disease (AD). Preservation of existing synapses and prevention of synaptic loss are promising strategies to preserve cognitive function in AD patients. As a potent natural anti-oxidant, a...

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Detalles Bibliográficos
Autores principales: Maiti, Panchanan, Bowers, Zackary, Bourcier-Schultz, Ali, Morse, Jarod, Dunbar, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871397/
https://www.ncbi.nlm.nih.gov/pubmed/33557949
http://dx.doi.org/10.1186/s13195-021-00769-9