Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection

BACKGROUND: The genomes of HIV-2 and some SIV strains contain the accessory gene vpx, which carries out several functions during infection, including the downregulation of SAMHD1. Vpx is also commonly used in experiments to increase HIV-1 infection efficiency in myeloid cells, particularly in studie...

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Detalles Bibliográficos
Autores principales: Cingöz, Oya, Arnow, Nicolas D., Puig Torrents, Mireia, Bannert, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871410/
https://www.ncbi.nlm.nih.gov/pubmed/33563288
http://dx.doi.org/10.1186/s12977-021-00548-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871410/
https://www.ncbi.nlm.nih.gov/pubmed/33563288
http://dx.doi.org/10.1186/s12977-021-00548-2

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