Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating

HIV-1 reverse transcription (RT) occurs before or during uncoating, but the cellular compartment where RT and uncoating occurs is unknown. Using imaging and biochemical assays to track HIV-1 capsids in the nucleus during infection, we demonstrated that higher-order capsid complexes and/or complete c...

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Detalles Bibliográficos
Autores principales: Selyutina, Anastasia, Persaud, Mirjana, Lee, Kyeongeun, KewalRamani, Vineet, Diaz-Griffero, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871456/
https://www.ncbi.nlm.nih.gov/pubmed/32997983
http://dx.doi.org/10.1016/j.celrep.2020.108201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871456/
https://www.ncbi.nlm.nih.gov/pubmed/32997983
http://dx.doi.org/10.1016/j.celrep.2020.108201

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