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Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating
HIV-1 reverse transcription (RT) occurs before or during uncoating, but the cellular compartment where RT and uncoating occurs is unknown. Using imaging and biochemical assays to track HIV-1 capsids in the nucleus during infection, we demonstrated that higher-order capsid complexes and/or complete c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871456/ https://www.ncbi.nlm.nih.gov/pubmed/32997983 http://dx.doi.org/10.1016/j.celrep.2020.108201 |