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Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?

Supplementing with creatine is very popular amongst athletes and exercising individuals for improving muscle mass, performance and recovery. Accumulating evidence also suggests that creatine supplementation produces a variety of beneficial effects in older and patient populations. Furthermore, evide...

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Autores principales: Antonio, Jose, Candow, Darren G., Forbes, Scott C., Gualano, Bruno, Jagim, Andrew R., Kreider, Richard B., Rawson, Eric S., Smith-Ryan, Abbie E., VanDusseldorp, Trisha A., Willoughby, Darryn S., Ziegenfuss, Tim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871530/
https://www.ncbi.nlm.nih.gov/pubmed/33557850
http://dx.doi.org/10.1186/s12970-021-00412-w
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author Antonio, Jose
Candow, Darren G.
Forbes, Scott C.
Gualano, Bruno
Jagim, Andrew R.
Kreider, Richard B.
Rawson, Eric S.
Smith-Ryan, Abbie E.
VanDusseldorp, Trisha A.
Willoughby, Darryn S.
Ziegenfuss, Tim N.
author_facet Antonio, Jose
Candow, Darren G.
Forbes, Scott C.
Gualano, Bruno
Jagim, Andrew R.
Kreider, Richard B.
Rawson, Eric S.
Smith-Ryan, Abbie E.
VanDusseldorp, Trisha A.
Willoughby, Darryn S.
Ziegenfuss, Tim N.
author_sort Antonio, Jose
collection PubMed
description Supplementing with creatine is very popular amongst athletes and exercising individuals for improving muscle mass, performance and recovery. Accumulating evidence also suggests that creatine supplementation produces a variety of beneficial effects in older and patient populations. Furthermore, evidence-based research shows that creatine supplementation is relatively well tolerated, especially at recommended dosages (i.e. 3-5 g/day or 0.1 g/kg of body mass/day). Although there are over 500 peer-refereed publications involving creatine supplementation, it is somewhat surprising that questions regarding the efficacy and safety of creatine still remain. These include, but are not limited to: 1. Does creatine lead to water retention? 2. Is creatine an anabolic steroid? 3. Does creatine cause kidney damage/renal dysfunction? 4. Does creatine cause hair loss / baldness? 5. Does creatine lead to dehydration and muscle cramping? 6. Is creatine harmful for children and adolescents? 7. Does creatine increase fat mass? 8. Is a creatine ‘loading-phase’ required? 9. Is creatine beneficial for older adults? 10. Is creatine only useful for resistance / power type activities? 11. Is creatine only effective for males? 12. Are other forms of creatine similar or superior to monohydrate and is creatine stable in solutions/beverages? To answer these questions, an internationally renowned team of research experts was formed to perform an evidence-based scientific evaluation of the literature regarding creatine supplementation.
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spelling pubmed-78715302021-02-09 Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? Antonio, Jose Candow, Darren G. Forbes, Scott C. Gualano, Bruno Jagim, Andrew R. Kreider, Richard B. Rawson, Eric S. Smith-Ryan, Abbie E. VanDusseldorp, Trisha A. Willoughby, Darryn S. Ziegenfuss, Tim N. J Int Soc Sports Nutr Review Supplementing with creatine is very popular amongst athletes and exercising individuals for improving muscle mass, performance and recovery. Accumulating evidence also suggests that creatine supplementation produces a variety of beneficial effects in older and patient populations. Furthermore, evidence-based research shows that creatine supplementation is relatively well tolerated, especially at recommended dosages (i.e. 3-5 g/day or 0.1 g/kg of body mass/day). Although there are over 500 peer-refereed publications involving creatine supplementation, it is somewhat surprising that questions regarding the efficacy and safety of creatine still remain. These include, but are not limited to: 1. Does creatine lead to water retention? 2. Is creatine an anabolic steroid? 3. Does creatine cause kidney damage/renal dysfunction? 4. Does creatine cause hair loss / baldness? 5. Does creatine lead to dehydration and muscle cramping? 6. Is creatine harmful for children and adolescents? 7. Does creatine increase fat mass? 8. Is a creatine ‘loading-phase’ required? 9. Is creatine beneficial for older adults? 10. Is creatine only useful for resistance / power type activities? 11. Is creatine only effective for males? 12. Are other forms of creatine similar or superior to monohydrate and is creatine stable in solutions/beverages? To answer these questions, an internationally renowned team of research experts was formed to perform an evidence-based scientific evaluation of the literature regarding creatine supplementation. BioMed Central 2021-02-08 /pmc/articles/PMC7871530/ /pubmed/33557850 http://dx.doi.org/10.1186/s12970-021-00412-w Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Antonio, Jose
Candow, Darren G.
Forbes, Scott C.
Gualano, Bruno
Jagim, Andrew R.
Kreider, Richard B.
Rawson, Eric S.
Smith-Ryan, Abbie E.
VanDusseldorp, Trisha A.
Willoughby, Darryn S.
Ziegenfuss, Tim N.
Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
title Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
title_full Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
title_fullStr Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
title_full_unstemmed Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
title_short Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
title_sort common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871530/
https://www.ncbi.nlm.nih.gov/pubmed/33557850
http://dx.doi.org/10.1186/s12970-021-00412-w
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