A poly-ADP-ribose polymer-based antibody-drug conjugate

Protein poly-ADP-ribosylation (PARylation) plays vital roles in many aspects of physiology and pathophysiology. This posttranslational modification is catalyzed by poly-ADP-ribose polymerases (PARPs) through additions of ADP-ribose from nicotinamide adenine dinucleotide (NAD(+)) to protein residues,...

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Detalles Bibliográficos
Autores principales: Shi, Xiaojing, Zhang, Xiao-Nan, Chen, Jingwen, Cheng, Qinqin, Pei, Hua, Louie, Stan G., Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871713/
https://www.ncbi.nlm.nih.gov/pubmed/33623656
http://dx.doi.org/10.1039/d0sc01795g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871713/
https://www.ncbi.nlm.nih.gov/pubmed/33623656
http://dx.doi.org/10.1039/d0sc01795g

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