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Ectopic CD137 expression by rhabdomyosarcoma provides selection advantages but allows immunotherapeutic targeting

Rhabdomyosarcoma (RMS) is a heterogeneous soft tissue neoplasm most frequently found in children and adolescents. As the prognosis for recurrent and metastatic RMS remains poor, immunotherapies are hoped to improve quality of life and survival. CD137 is a member of tumor necrosis factor receptor fam...

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Detalles Bibliográficos
Autores principales: Lee, Kang Yi, Wong, Hiu Yi, Zeng, Qun, Le Lin, Jia, Cheng, Man Si, Kuick, Chik Hong, Chang, Kenneth Tou En, Loh, Amos Hong Pheng, Schwarz, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872024/
https://www.ncbi.nlm.nih.gov/pubmed/33643694
http://dx.doi.org/10.1080/2162402X.2021.1877459