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Ectopic CD137 expression by rhabdomyosarcoma provides selection advantages but allows immunotherapeutic targeting
Rhabdomyosarcoma (RMS) is a heterogeneous soft tissue neoplasm most frequently found in children and adolescents. As the prognosis for recurrent and metastatic RMS remains poor, immunotherapies are hoped to improve quality of life and survival. CD137 is a member of tumor necrosis factor receptor fam...
Autores principales: | Lee, Kang Yi, Wong, Hiu Yi, Zeng, Qun, Le Lin, Jia, Cheng, Man Si, Kuick, Chik Hong, Chang, Kenneth Tou En, Loh, Amos Hong Pheng, Schwarz, Herbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872024/ https://www.ncbi.nlm.nih.gov/pubmed/33643694 http://dx.doi.org/10.1080/2162402X.2021.1877459 |
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