Specific protein kinase C isoform exerts chronic inhibition on the slowly activating delayed-rectifier potassium current by affecting channel trafficking

The slowly activating delayed rectifier K(+) current (I(Ks)) plays a key role in the repolarization of ventricular action potential in the human heart and is formed by the pore-forming α-subunit encoded by KCNQ1 (Kv7.1) and β-subunit encoded by KCNE1. Evidence suggested that I(Ks) was regulated thro...

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Detalles Bibliográficos
Autores principales: Gou, Xiangbo, Hu, Tingting, Gou, Yu, Li, Chaoqi, Yi, Ming, Jia, Mengran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872027/
https://www.ncbi.nlm.nih.gov/pubmed/33535882
http://dx.doi.org/10.1080/19336950.2021.1882112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872027/
https://www.ncbi.nlm.nih.gov/pubmed/33535882
http://dx.doi.org/10.1080/19336950.2021.1882112

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