Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is associated with highly immunosuppressive tumor microenvironment (TME) that can limit the efficacy of dendritic cell (DC) vaccine immunotherapy. Irreversible electroporation (IRE) is a local ablation approach. Herein, we test the hypothesis that IRE ablation...

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Detalles Bibliográficos
Autores principales: Yang, Jia, Eresen, Aydin, Shangguan, Junjie, Ma, Quanhong, Yaghmai, Vahid, Zhang, Zhuoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872063/
https://www.ncbi.nlm.nih.gov/pubmed/33643692
http://dx.doi.org/10.1080/2162402X.2021.1875638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872063/
https://www.ncbi.nlm.nih.gov/pubmed/33643692
http://dx.doi.org/10.1080/2162402X.2021.1875638

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