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Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is associated with highly immunosuppressive tumor microenvironment (TME) that can limit the efficacy of dendritic cell (DC) vaccine immunotherapy. Irreversible electroporation (IRE) is a local ablation approach. Herein, we test the hypothesis that IRE ablation...
Autores principales: | Yang, Jia, Eresen, Aydin, Shangguan, Junjie, Ma, Quanhong, Yaghmai, Vahid, Zhang, Zhuoli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872063/ https://www.ncbi.nlm.nih.gov/pubmed/33643692 http://dx.doi.org/10.1080/2162402X.2021.1875638 |
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