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Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients
The understanding of the role of B cells in patients with solid tumors remains insufficient. We found that circulating B cells produced TNFα and/or IL-6, associated with unresponsiveness and poor overall survival of melanoma patients treated with anti-CTLA4 antibody. Transcriptome analysis of B cell...
Päätekijät: | , , , , , , , , , , |
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Aineistotyyppi: | Online Artikkeli Teksti |
Kieli: | English |
Julkaistu: |
Taylor & Francis
2021
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Aiheet: | |
Linkit: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872097/ https://www.ncbi.nlm.nih.gov/pubmed/33643691 http://dx.doi.org/10.1080/2162402X.2021.1873585 |