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Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients

The understanding of the role of B cells in patients with solid tumors remains insufficient. We found that circulating B cells produced TNFα and/or IL-6, associated with unresponsiveness and poor overall survival of melanoma patients treated with anti-CTLA4 antibody. Transcriptome analysis of B cell...

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Detalles Bibliográficos
Autores principales:	de Jonge, Kaat, Tillé, Laure, Lourenco, Joao, Maby-El Hajjami, Hélène, Nassiri, Sina, Racle, Julien, Gfeller, David, Delorenzi, Mauro, Verdeil, Grégory, Baumgaertner, Petra, Speiser, Daniel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872097/ https://www.ncbi.nlm.nih.gov/pubmed/33643691 http://dx.doi.org/10.1080/2162402X.2021.1873585

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