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A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation

Intestinal organoids are an excellent model to study epithelial biology. Yet, the selection of analytical tools to accurately quantify heterogeneous organoid cultures remains limited. Here, we developed a semi-automated organoid screening method, which we applied to a library of highly specific chem...

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Detalles Bibliográficos
Autores principales: Ostrop, Jenny, Zwiggelaar, Rosalie T., Terndrup Pedersen, Marianne, Gerbe, François, Bösl, Korbinian, Lindholm, Håvard T., Díez-Sánchez, Alberto, Parmar, Naveen, Radetzki, Silke, von Kries, Jens Peter, Jay, Philippe, Jensen, Kim B., Arrowsmith, Cheryl, Oudhoff, Menno J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872100/
https://www.ncbi.nlm.nih.gov/pubmed/33575256
http://dx.doi.org/10.3389/fcell.2020.618552