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Personalized logical models to investigate cancer response to BRAF treatments in melanomas and colorectal cancers

The study of response to cancer treatments has benefited greatly from the contribution of different omics data but their interpretation is sometimes difficult. Some mathematical models based on prior biological knowledge of signaling pathways facilitate this interpretation but often require fitting...

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Detalles Bibliográficos
Autores principales: Béal, Jonas, Pantolini, Lorenzo, Noël, Vincent, Barillot, Emmanuel, Calzone, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872233/
https://www.ncbi.nlm.nih.gov/pubmed/33507915
http://dx.doi.org/10.1371/journal.pcbi.1007900