The NF-κB regulator Bcl-3 restricts terminal differentiation and promotes memory cell formation of CD8(+) T cells during viral infection

Bcl-3 is an atypical member of the IκB family that acts in the nucleus to modulate transcription of many NF-κB targets in a highly context-dependent manner. Accordingly, complete Bcl-3(-/-) mice have diverse defects in both innate and adaptive immune responses; however, direct effects of Bcl-3 actio...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaiswal, Hemant, Ciucci, Thomas, Wang, Hongshan, Tang, Wanhu, Claudio, Estefania, Murphy, Philip M., Bosselut, Rémy, Siebenlist, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872245/
https://www.ncbi.nlm.nih.gov/pubmed/33508001
http://dx.doi.org/10.1371/journal.ppat.1009249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872245/
https://www.ncbi.nlm.nih.gov/pubmed/33508001
http://dx.doi.org/10.1371/journal.ppat.1009249

Ejemplares similares