Modeling Bioavailable Concentrations in Zebrafish Cell Lines and Embryos Increases the Correlation of Toxicity Potencies across Test Systems

[Image: see text] Linking cellular toxicity to low-tier animal toxicity and beyond is crucial within the adverse outcome pathway concept and the 3R framework. This study aimed to determine and compare the bioavailable effect concentrations in zebrafish cell lines and embryos. Acute, short-term toxic...

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Detalles Bibliográficos
Autores principales: Lungu-Mitea, Sebastian, Vogs, Carolina, Carlsson, Gunnar, Montag, Maximiliane, Frieberg, Kim, Oskarsson, Agneta, Lundqvist, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872314/
https://www.ncbi.nlm.nih.gov/pubmed/33320646
http://dx.doi.org/10.1021/acs.est.0c04872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872314/
https://www.ncbi.nlm.nih.gov/pubmed/33320646
http://dx.doi.org/10.1021/acs.est.0c04872

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