Cargando…

Prerecognition Diffusion Mechanism of Human DNA Mismatch Repair Proteins along DNA: Msh2-Msh3 versus Msh2-Msh6

[Image: see text] DNA mismatch repair (MMR) is an important postreplication process that eliminates mispaired or unpaired nucleotides to ensure genomic replication fidelity. In humans, Msh2-Msh6 and Msh2-Msh3 are the two mismatch repair initiation factors that recognize DNA lesions. While X-ray crys...

Descripción completa

Detalles Bibliográficos
Autores principales: Pal, Arumay, Greenblatt, Harry M., Levy, Yaakov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872316/
https://www.ncbi.nlm.nih.gov/pubmed/33319999
http://dx.doi.org/10.1021/acs.biochem.0c00669