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Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer

Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signatures’ that have led to key insights into cancer etiolog...

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Detalles Bibliográficos
Autores principales: Afsari, Bahman, Kuo, Albert, Zhang, YiFan, Li, Lu, Lahouel, Kamel, Danilova, Ludmila, Favorov, Alexander, Rosenquist, Thomas A, Grollman, Arthur P, Kinzler, Ken W, Cope, Leslie, Vogelstein, Bert, Tomasetti, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872524/
https://www.ncbi.nlm.nih.gov/pubmed/33491650
http://dx.doi.org/10.7554/eLife.61082