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Pretreatment with S-Nitrosoglutathione Attenuates Septic Acute Kidney Injury in Rats by Inhibiting Inflammation, Oxidation, and Apoptosis

OBJECTIVE: We aimed to investigate the protective effect of s-nitrosoglutathione (SNG) pretreatment on acute kidney injury (AKI) in septic rats. METHODS: We constructed a rat model of sepsis by cecal ligation and puncture and observed the survival of the rats. We obtained kidney and blood samples fr...

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Detalles Bibliográficos
Autores principales: Fan, Heng, Le, Jian-wei, Sun, Min, Zhu, Jian-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872741/
https://www.ncbi.nlm.nih.gov/pubmed/33604382
http://dx.doi.org/10.1155/2021/6678165