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A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma

Cytochrome P450 2E1 (CYP2E1) is a key target protein in the development of alcoholic and nonalcoholic fatty liver disease (FLD). The pathophysiological correlate is the massive production of reactive oxygen species. The role of CYP2E1 in the development of hepatocellular carcinoma (HCC), the final c...

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Detalles Bibliográficos
Autores principales: Diesinger, Torsten, Lautwein, Alfred, Bergler, Sebastian, Buckert, Dominik, Renz, Christian, Dvorsky, Radovan, Buko, Vyacheslav, Kirko, Siarhei, Schneider, Edith, Kuchenbauer, Florian, Kumar, Mukesh, Günes, Cagatay, Genze, Felicitas, Büchele, Berthold, Simmet, Thomas, Haslbeck, Martin, Masur, Kai, Barth, Thomas, Müller-Enoch, Dieter, Wirth, Thomas, Haehner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872744/
https://www.ncbi.nlm.nih.gov/pubmed/33604316
http://dx.doi.org/10.1155/2021/8854432